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SKU: E-AB-13288_20μL-ES
ZNF395 Polyclonal Antibody, 20 μL
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3’-CCGG-5’ sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.8 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Epigenetics and Nuclear Signaling;Microbiology
Species Reactivity:Human
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Target Synonym:DKFZp434K1210;HD gene regulatory region binding protein 2;HD gene regulatory region-binding protein 2;HD-regulating factor 2;HDBP-2;HDBP2;HDRF-2;Huntington disease gene regulatory region-binding protein 2;Huntington's disease gene regulatory region binding protein 2;Papillomavirus regulatory factor 1;papillomavirus regulatory factor PRF 1;Papillomavirus-binding factor;PBF;PRF-1;PRF1;PTTG1IP;Si-1-8-14;Zinc finger protein 395;ZN395;znf395
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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