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SKU: E-AB-19204_120μL-ES
TNNT1 Polyclonal Antibody, 120 μL
This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1.32 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Application:IHC
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Research Areas:Signal transduction
Species Reactivity:Human
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Target Synonym:ANM; MGC104241; NEM5; Skeletal; Slow ; slow skeletal muscle; Slow skeletal muscle troponin T; sTnT; Tnnt1; TNNT1; TNT; TnTs; Troponin T; Troponin T slow skeletal muscle; Troponin T type 1 (skeletal slow); troponin T1 skeletal slow; Troponin T1; slow skeletal type
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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