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SKU: E-AB-14348_120μL-ES
SLC4A4 Polyclonal Antibody, 120 μL
This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. Sodium bicarbonate cotransporters (NBCs) mediate the coupled movement of sodium and bicarbonate ions across the plasma membrane of many cells. This is an electrogenic process with an apparent stoichiometry of 3 bicarbonate ions per sodium ion. Sodium bicarbonate cotransport is involved in bicarbonate secretion/absorption and intracellular pH regulation. Romero and Boron (1999) reviewed NBCs. Soleimani and Burnham (2000) reviewed NBCs and their regulation in physiologic and pathophysiologic states.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.4 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Metabolism;Neuroscience;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:DKFZp781H1314;Electrogenic sodium bicarbonate cotransporter 1;hhNMC;HNBC 1;HNBC1;kNBC 1;KNBC;kNBC1;Na(+)/HCO3(-) cotransporter;Na+HCO3- cotransporter 4;NBC 1;NBC 2;NBC1;NBC2;Nbc4;NBCE 1;NBCE1;OTTHUMP00000160355;OTTHUMP00000218884;OTTHUMP00000218885;PNBC;S4A4;SLC4A4;SLC4A5;Sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter;kidney;sodium bicarbonate cotransporter;pancreas);Sodium bicarbonate cotransporter;Sodium bicarbonate cotransporter kidney;sodium bicarbonate cotransporter member 4;Sodium bicarbonate cotransporter pancreas;Solute carrier family 4 member 4;Solute carrier family 4 sodium bicarbonate cotransporter member 4;Solute carrier family 4 sodium bicarbonate cotransporter member 5;Solute carrier family 4;sodium bicarbonate cotransporter;member 4;brain type
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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