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SKU: D-AB-10209L_25μL-ES
Serpina1 Polyclonal Antibody, 25 μL
SERPINA1 is the gene for a protein called alpha-1-antitrypsin (AAT),which is a serine protease inhibitor whose targets include elastase,plasmin,thrombin,trypsin,chymotrypsin,and plasminogen activator. AAT is a glycoprotein synthesized primarily by hepatocytes,with smaller amountssynthesized by intestinal epithelial cells,neutrophils,pulmonary alveolar cells and macrophages. AAT is the most abundant,endogenous serine protease inhibitor in blood circulation and it has been implicated in regulating vital fluid phase biological events such as blood coagulation,fibrinolysis,complement activation,apoptosis,reproduction,tumor progression and inflammatory response. The primary function of AAT is thought to be the inactivation of neutrophil elastase and other endogenous serine proteases. Defects in SERPINA1 can cause emphysema or liver disease.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:46kDa
Observed Molecular Weight:43kDa,50kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:46kDa
Dilution:WB 1:500-1000
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Application:WB
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Research Areas:Cancer;Cardiovascular;Metabolism
Species Reactivity:Human;Mouse;Rat
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Target Synonym:A1A;A1AT;A1AT;AAT;Alpha 1 antiproteinase;Alpha 1 antitrypsin;Alpha 1 antitrypsin null;Alpha 1 protease inhibitor;Alpha-1 protease inhibitor;Alpha-1-antiproteinase;alpha1 proteinase inhibitor;Alpha1AT;Dom1;PI;PI1;PRO2275;Serine (or cysteine) proteinase inhibitor clade A member 1;Serine protease inhibitor 1-1;Serine protease inhibitor A1a;Serpin A1;Serpin A1a;Serpin peptidase inhibitor clade A member 1;Serpina1;Short peptide from AAT;SPAAT;Spi1-1
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Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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