- Specification
- Downloads
- Reviews
$205.92
ADD TO CART
SKU: E-AB-10457_60μL-ES
RPSA Polyclonal Antibody, 60 μL
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene
- Regular price
- $205.92 USD
- Sale price
- $205.92 USD
- Regular price
-
ADD TO CART
Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
Safety Performance:
Protection Class:
Sterile Status:
Reconstitution:
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Battery:
Battery Service Life:
Component:
Technical Specifications
Capacity:
Concentration:0.3 mg/mL
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:33kDa
Observed Molecular Weight:
Purity:
Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:33kDa
Dilution:WB 1:500-1:2000
Driving Motor DC motor:
Em:
Ex:
Endotoxin:
Flow rate [liquid]:
Features and Capabilities
Application:WB
Detection Target:
Detection Type:
Detection Range:
Research Areas:Cancer;Cardiovascular;Neuroscience;Signal Transduction
Species Reactivity:Human;Mouse;Rat
Reactivity:
Target Synonym:34/67 kDa laminin receptor;37 kDa laminin receptor precursor;37/67 kDa laminin receptor;37LRP;40S ribosomal protein SA;67 kDa laminin receptor;67LR;Colon carcinoma laminin binding protein;Colon carcinoma laminin-binding protein;LAMBR;Laminin receptor 1;Laminin-binding protein precursor p40;LAMR 1;LamR;LAMR1;LBP;LBP/p40;LRP;LRP/LR;Multidrug resistance associated protein MGr1 Ag;Multidrug resistance associated protein MGr1Ag;Multidrug resistance-associated protein MGr1-Ag;NEM/1CHD4;p40;Ribosomal Protein SA;rpsA;RSSA;SA
Test Principle:
Quantitative/Qualitative :
Result Type:
Materials :
Assay Time:
Autoclave component:
Available Rotor Adapters:
Binding Capacity:
Bio-activity:
Bottom Shape:
Bottom Type:
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Cap Color:
Clonality:Polyclonal
Conjugation:Unconjugated
Coupled Ligand:
Cover Type:
Detection Instrument :
Dispensing Speed:
Display:
Form:
Formulation:
Graduation:
Growth Area:
Powered by Bioz