SKU: E-AB-18867_200μL-ES

RFX6 Polyclonal Antibody, 200 μL

The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:0.96 mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IHC 1:50-1:300

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Application:IHC

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Research Areas:Epigenetics and Nuclear Signaling

Species Reactivity:Human;Mouse

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Target Synonym:DNA binding protein RFX6 ; Regulatory factor X domain containing protein 1; RFX6; RFX6 regulatory factor X; 6

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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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