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SKU: PKSH030339_50μg-ES
Recombinant Human TLK1/PKU-beta Protein (His & GST Tag), 50 μg
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Safety Performance:
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Sterile Status:
Reconstitution:Not Applicable
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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Calculated Molecular Weight:114 kDa
Observed Molecular Weight:125 kDa
Purity: > 88 % as determined by reducing SDS-PAGE.
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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Calculated Molecular Weight:114 kDa
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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
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Features and Capabilities
Application:Enzyme
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Research Areas:Epigenetics and Nuclear Signaling,Signal Transduction
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Bio-activity:The specific activity was determined to be 1. 6 nmol/min/mg using Histone H3 protein as substrate.
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Formulation:Supplied as sterile solution of 20mM Tris, 500mM NaCl, pH 7.4, 10% glycerol
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