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SKU: PKSH031127_50μg-ES
Recombinant Human SULT2B1 Protein (aa 2-365, His Tag), 50 μg
Sulfotransferase family cytosolic 2B member 1; also known as Sulfotransferase 2B1; ST2B1; Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2; SULT2B1 and HSST2; is a cytoplasm protein which belongs to thesulfotransferase 1 family. The human hydroxysteroid sulfotransferase (SULT) family is comprised of two subfamilies; SULT2A1 and SULT2B1. SULT2B1 is expressed highly in placenta; prostate and trachea. A lesser expression of SULT1B1 was observed in the small intestine and lung. SULT2B1 catalyzes the sulfate conjugation of many hormones; neurotransmitters; drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds; and therefore their renal excretion; but it can also result in bioactivation to form active metabolites. SULT2B1 sulfates hydroxysteroids like DHEA. Isoform1 preferentially sulfonates cholesterol. The two SULT2B1 isoforms; SULT2B1a and SULT2B1b; are encoded by a single gene as a result of alternative transcription initiation and alternative splicing. SULT2B1b catalyzes the sulfonation of 3beta-hydroxysteroid hormones and cholesterol; whereas SULT2B1a preferentially catalyzes pregnenolone sulfonation.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Reconstitution:Please refer to the printed manual for detailed information.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
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Calculated Molecular Weight:42 kDa
Observed Molecular Weight:44 kDa
Purity: > 76 % as determined by reducing SDS-PAGE.
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Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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Calculated Molecular Weight:42 kDa
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Research Areas:Signal Transduction;Cardiovascular;Cancer;metabolism;
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Bio-activity:Not validated for activity
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Formulation:Lyophilized from sterile 20mM Tris, 0.1M NaCl, 10% glycerol, pH 8.0
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
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