SKU: PDMH100321_20μg-ES

Recombinant Human SP-A1 Protein(Fc Tag), 20 μg

Surfactant protein A (SFTPA1) , a member of the collagenous lectin (collectin) family , was first described as a major constituent of lung surfactant but has recently also been found in the female genital tract. Various microorganisms colonize this area and may cause intrauterine infection or trigger preterm labor. The Human SFTPA1 and SFTPA2 genes encode SP-A1 and SP-2 proteins , and each gene has been identified with numerous genetic variants. SP-A1 and SP-A2 differentially enhance bacterial phagocytosis. Sex differences have been observed in pulmonary disease and survival of wild type and SP-A knockout (KO) mice. SP-A interacts and regulates many of the functions of alveolar macrophages (AM). It is shown that SP-A variants differ in their ability to regulate the AM miRNome in response to oxidative stress (OxS).

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

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Calculated Molecular Weight:49.9 kDa

Observed Molecular Weight:60 kDa

Purity: > 90% as determined by reducing SDS-PAGE.

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Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

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Calculated Molecular Weight:49.9 kDa

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Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

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Research Areas:Signal Transduction;Tags & Cell Markers;Cell Biology;Metabolism

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Bio-activity:Not validated for activity

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Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

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