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SKU: PDEH100478_20μg-ES
Recombinant Human ISG15 Protein(Sumo Tag), 20 μg
ISG15 (interferon-induced 15 kDa protein, also known as IP17) is a 15 kDa ubiquitin family protein that is expressed by a wide variety of cell types. ISG15 is induced by type-I IFN, and like ubiquitin, becomes conjugated to intracellular proteins. Unlike ubiquitin, it does not target proteins for degradation. Instead, it is part of the antivirus response. Human proISG15 is 165 amino acids (aa) in length. There are two ubiquitin-like domains (aa 2-78 and 79-157) and a propeptide (aa 158-165) that is cleaved intracellularly. Select blood mononuclear cells secrete mature ISG15, which is chemotactic for neutrophils. Mature Human ISG15 is 66% aa identical to Mouse ISG15.
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Brands:Elabscience
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