SKU: PKSH033679_50μg-ES

Recombinant Human FGL1 Protein (mFc Tag), 50 μg

Hepassocin; also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1); is a liver-specific secreted protein belonging to the fibronogen superfamily; whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Reconstitution:Please refer to the printed manual for detailed information.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

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Calculated Molecular Weight:60.6 kDa

Observed Molecular Weight:60-65 kDa

Purity: > 95 % as determined by reducing SDS-PAGE.

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Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

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Calculated Molecular Weight:60.6 kDa

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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

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Application:ELISA

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Research Areas:Cardiovascular

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Bio-activity:Immobilized Human LAG-3(Cat: PKSH033596) at 5μg/ml(100 μl/well) can bind Human FGL1-Fc. The ED50 of Human FGL1-Fc is 30-90 ng/ml.

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Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

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