SKU: PKSH032319_10μg-ES

Recombinant Human Cystathionine γ-Lyase/CTH Protein, 10 μg

Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Reconstitution:Not Applicable

Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

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Calculated Molecular Weight:44.7 kDa

Observed Molecular Weight:38-50 kDa

Purity: > 85 % as determined by reducing SDS-PAGE.

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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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Calculated Molecular Weight:44.7 kDa

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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

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Research Areas:Signal Transduction;Cancer;metabolism;

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Bio-activity:Not validated for activity

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Formulation:Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH8.0.

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