SKU: PKSH032079_50μg-ES

Recombinant Human AGR2 Protein (His Tag), 50 μg

Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Sterile Status:

Reconstitution:Not Applicable

Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

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Calculated Molecular Weight:18.9 kDa

Observed Molecular Weight:18 kDa

Purity: > 95 % as determined by reducing SDS-PAGE.

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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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Calculated Molecular Weight:18.9 kDa

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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

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Research Areas:Signal Transduction;Cancer;Developmental Biology;Stem cells

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Bio-activity:Not validated for activity

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Formulation:Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 10%Glycerol, 0.01%Tween 80, pH8.0.

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