SKU: PKSH032032_50μg-ES

Recombinant Human ACADM/MCAD Protein (His Tag), 50 μg

Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. ACADM is specific for acyl chain lengths of 4 to 16. It is essential for converting these particular fatty acids to energy, especially during fasting periods. Defects in ACADM cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Sterile Status:

Reconstitution:Not Applicable

Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

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Calculated Molecular Weight:45.9 kDa

Observed Molecular Weight:42 kDa

Purity: > 95 % as determined by reducing SDS-PAGE.

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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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Calculated Molecular Weight:45.9 kDa

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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

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Research Areas:Signal Transduction;Cardiovascular;Cancer;metabolism;

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Bio-activity:Not validated for activity

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Formulation:Supplied as a 0.2 μm filtered solution of 20mM Acetate, 10% Trehalose, 0.05% Tween 80, pH 5.0.

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