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SKU: E-AB-10571_120μL-ES
PTCH1 Polyclonal Antibody, 120 μL
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:0.5 mg/mL
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Calculated Molecular Weight:161kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:161kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:200
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Features and Capabilities
Application:WB;IHC
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Research Areas:Cancer;Cell Biology;Neuroscience;Stem Cells
Species Reactivity:Human;Mouse
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Target Synonym:PTC;BCNS;HPE7;PTC1;PTCH;NBCCS;PTCH11
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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