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SKU: E-AB-64500_200μL-ES
PIWIL4 Polyclonal Antibody, 200 μL
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1mg/mL
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Calculated Molecular Weight:52kDa/56kDa/96kDa
Observed Molecular Weight:105kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:52kDa/56kDa/96kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse;Rat
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Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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