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SKU: E-AB-21179_200μL-ES
Phospho-PAK1 (Thr212) Polyclonal Antibody, 200 μL
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:61kDa
Observed Molecular Weight:65kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:61kDa
Dilution:WB 1:500-1:2000;IHC 1:100-1:300
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Application:WB;IHC-p
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Research Areas:Cancer;Cell Biology;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:ADRB2;Alpha PAK;Alpha-PAK;MGC130000;MGC130001;p21 activated kinase 1;p21 protein (Cdc42/Rac) activated kinase 1;p21-activated kinase 1;p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related);p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog;yeast);p65 PAK;p65-PAK;P68-PAK;PAK alpha;PAK-1;Pak1;PAK1;Paka;PAKalpha;Protein kinase MUK2;Rac/p21-activated kinase;Serine/threonine-protein kinase PAK 1;STE20 homolog yeast
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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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