SKU: E-AB-20888_120μL-ES

Phospho-HDAC5 (Ser498) Polyclonal Antibody, 120 μL

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1 mg/mL

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Calculated Molecular Weight:122kDa

Observed Molecular Weight:122kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:122kDa

Dilution:WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000

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Features and Capabilities

Application:WB;IHC-p;IF

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Research Areas:Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Stem Cells

Species Reactivity:Human;Mouse

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Target Synonym:Antigen NY CO 9;Antigen NY-CO-9;HD5;HDAC 5;HDAC5;HDAC5;Histone deacetylase 5;NY CO 9

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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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