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SKU: E-AB-20843_20μL-ES
Phospho-CHEK2 (Thr68) Polyclonal Antibody, 20 μL
Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:61kDa
Observed Molecular Weight:61kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:61kDa
Dilution:WB 1:500-1:2000;IHC 1:100-1:300;IF 1:50-1:200
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Application:WB;IHC-p;IF
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Research Areas:Cancer;Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse;Rat
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Target Synonym:CDS 1;Cds1;Cds1 homolog;Checkpoint kinase 2;Checkpoint like protein CHK2;CHEK 2;Chek2;Chk 2;CHK2 checkpoint homolog (S. pombe);CHK2 checkpoint homolog;CHK2;hCds1;HuCds 1;LFS 2;LFS2;PP1425;RAD 53;RAD53;Rad53 homolog;Serine/threonine protein kinase Chk2;Serine/threonine-protein kinase Chk2
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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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