- Specification
- Downloads
- Reviews
$3,644.57
ADD TO CART
SKU: AN000280P_1mg-ES
Pentraxin 3/TSG-14 Polyclonal Antibody(Capture/Detector), 1 mg
Pentraxin 3 (PTX3),TSG-14,was initially identified as a TNF-alpha or Il-1 beta inducible gene. It belongs to the pentraxin family,which was named originally for the homo-pentameric structure formed by its members. The pentraxin family is divided into two subfamilies: the “short” and the “long” pentraxins with approximate molecular weights of 25 kDa and 50 kDa,respectively. TSG-14 is a member of the long pentraxin subfamily,which also includes the Xenopus laevis Xl-PXN1,the guinea pig apexin/p50,the rat neuronal pentraxin I (NPI) and NPR,the human neuronal pentraxin II (NPTX2) and the human neuronal activity-related pentraxin.Mature secreted TSG-14 contains a pentaxin-like domain at its carboxy-terminus that shares 23?28% amino acid (aa) sequence similarity to C-reactive protein (CRP) and serum amyloid P component (SAP),which belongs to the short pentraxin subfamily. However,the N-terminal sequence of TSG-14 does not share aa sequence homology with any of the “short” pentaxins. Unlike CRP and SAP,which forms pentamers only,TSG-14 forms both pentameric and higher ordered oligomers. Similarly to CRP and SAP,TSG-14 binds to the complement cascade component C1q. However,TSG-14 does not bind to phosphoethanolamine,phosphocholine,or high pyruvate agarose,which are known ligands for CRP and SAP. TSG-14 is a marker of the acute phase response and is highly expressed in advanced atherosclerotic plaques. While CRP and SAP are primarily produced in the liver,TSG-14 expression is strongly up?regulated by TNF-alpha,Il-1 beta,and bacterial lPS in peripheral fibroblasts,endothelial cells,and macrophages.
- Regular price
- $3,644.57 USD
- Sale price
- $3,644.57 USD
- Regular price
-
ADD TO CART
Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
Safety Performance:
Protection Class:
Sterile Status:
Reconstitution:
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Battery:
Battery Service Life:
Component:
Technical Specifications
Capacity:
Concentration:1 mg/mL
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:
Observed Molecular Weight:
Purity:
Shelf Life:12 months
Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:
Dilution:ELISA Capture 2-8 μg/mL;ELISA Detector 0.1-0.4 μg/mL
Driving Motor DC motor:
Em:
Ex:
Endotoxin:
Flow rate [liquid]:
Features and Capabilities
Application:ELISA Capture/Detector
Detection Target:
Detection Type:
Detection Range:
Research Areas:
Species Reactivity:Rat
Reactivity:
Target Synonym:Ptx3;Ptx-3;Pentraxin 3
Test Principle:
Quantitative/Qualitative :
Result Type:
Materials :
Assay Time:
Autoclave component:
Available Rotor Adapters:
Binding Capacity:
Bio-activity:
Bottom Shape:
Bottom Type:
Buffer:Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
Cap Color:
Clonality:Polyclonal
Conjugation:Unconjugated
Coupled Ligand:
Cover Type:
Detection Instrument :
Dispensing Speed:
Display:
Form:
Formulation:
Graduation:
Growth Area:
Powered by Bioz