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SKU: E-AB-13305_60μL-ES
NRG1 Polyclonal Antibody, 60 μL
The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD).
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.8 mg/mL
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Calculated Molecular Weight:70kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:70kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Neuroscience;Signal Transduction
Species Reactivity:Human
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Target Synonym:Acetylcholine receptor-inducing activity;Acetylcholine receptor-inducing activity;CHICK;homolog of;ARIA;Breast cancer cell differentiation factor p45;GGF;GGF2;Glial growth factor;Heregulin;heregulin;alpha (45kD;ERBB2 p185-activator);HGL;HRG;HRG1;HRGA;MST131;NDF;Neu differentiation factor;Neuregulin 1;neuregulin 1 type IV beta 1a;neuregulin 1 type IV beta 3;Neuregulin-1;NRG 1;nrg1;NRG1-IT2;NRG1;OTTHUMP00000225398;OTTHUMP00000225419;OTTHUMP00000225420;OTTHUMP00000225421;OTTHUMP00000225422;OTTHUMP00000225477;OTTHUMP00000225545;OTTHUMP00000230603;OTTHUMP00000230605;pro-neuregulin-1;membrane-bound isoform;Pro-NRG1;ProNRG1;Sensory and motor neuron-derived factor;SMDF
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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