SKU: E-AB-11440_60μL-ES

NEDD4L Polyclonal Antibody, 60 μL

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:0.4 mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IHC 1:100-1:300

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Application:IHC

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Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling

Species Reactivity:Human;Mouse

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Target Synonym:E3 ubiquitin protein ligase NEDD4 like protein;E3 ubiquitin-protein ligase NEDD4-like;KIAA0439;NED4L;NEDD4 2;NEDD4 2c;Nedd4-2;NEDD4-2a;NEDD4.2;NEDD4b;NEDD4L;NEDD4La;NEDD4Lb;NEDD4Lc;NEDD4Ld;NEDD4Le;NEDD4Lf;NEDD4Lg;NEDD4Lh;NEDL3;Neural precursor cell expressed developmentally down regulated 4 like E3 ubiquitin protein ligase;Neural precursor cell expressed;developmentally down regulated 4 like;RSP5;Ubiquitin protein ligase Rsp5

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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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