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SKU: E-AB-12802_60μL-ES
MDC1 Polyclonal Antibody, 60 μL
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1.2 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:100-1:300
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Application:IHC
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Research Areas:Cancer;Epigenetics and Nuclear Signaling
Species Reactivity:Human
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Target Synonym:Homologue to Drosophila photoreceptor protein calphotin;MDC 1;Mdc1;MDC1;Mediation of DNA damage checkpoint 1;Mediator of DNA damage checkpoint 1;Mediator of DNA damage checkpoint protein 1;NFBD 1;NFBD1;Nuclear factor with BRCT domains 1;Nuclear Factor with BRCT Domains Protein 1
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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