SKU: E-AB-13399_120μL-ES

MAGEL2 Polyclonal Antibody, 120 μL

Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:0.8 mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IHC 1:50-1:200

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Application:IHC

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Research Areas:Cancer;Immunology

Species Reactivity:Human

Reactivity:

Target Synonym:Mage-l2;MAGE-like 2;MAGE-like protein 2;MAGEL2;melanoma antigen-like gene 2;NDNL1;Necdin like protein 1;necdin-like 1;nM15;ns7;Protein nM15;PWLS

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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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