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SKU: E-AB-13360_200μL-ES
KDM5B Polyclonal Antibody, 200 μL
PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1.5 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse
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Target Synonym:Cancer/testis antigen 31;CT31;Histone demethylase JARID1B;JARID1B;Jumonji AT rich interactive domain 1B;Jumonji/ARID domain-containing protein 1B;Kdm5b;KDM5B;Lysine (K) specific demethylase 5B;Lysine demethylase 5B;Lysine specific demethylase 5B;Lysine-specific demethylase 5B;PLU-1;PLU1;PPP1R98;Protein phosphatase 1 regulatory subunit 98;PUT1;putative DNA/chromatin binding motif;RBBP2H1A;RBP2 like;RBP2-H1;Retinoblastoma-binding protein 2 homolog 1;Retinoblastoma-binding protein 2 homolog 1A
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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