SKU: AN005830L_100μL-ES

IL-27B Polyclonal Antibody, 100 μL

Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

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Concentration:1 mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.

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Application:IHC

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Research Areas:Immunology

Species Reactivity:Human

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Target Synonym:EBI;EBI3;IL27;IL35;IL27B;Interleukin-27 subunit beta

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Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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