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SKU: AN000230P_25μg-ES
IL-18/IL-1F4 Polyclonal Antibody(Capture/Detector), 25 μg
Pro-inflammatory cytokine primarily involved in epithelial barrier repair,polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.Upon binding to Il18R1 and Il18RAP,forms a signaling ternary complex which activates NF-kappa-B,triggering synthesis of inflammatory mediators.Synergizes with Il12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Shelf Life:12 months
Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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Dilution:ELISA Capture 2-8 μg/mL;ELISA Detector 0.1-0.4 μg/mL
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Application:ELISA Capture/Detector
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Research Areas:Immunology;Cancer;Metabolism
Species Reactivity:Human
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Target Synonym:IL18;IL-18; IGIF; IL1F4;Iboctadekin;Interferon gamma-inducing factor;InterLeukin-1 gamma (IL-1 gamma)
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Buffer:Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
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Clonality:Polyclonal
Conjugation:Unconjugated
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