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SKU: E-AB-11319_60μL-ES
IDH2 Polyclonal Antibody, 60 μL
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.3 mg/mL
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Calculated Molecular Weight:51kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:51kDa
Dilution:WB 1:500-1:2000;IHC 1:100-1:300
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Application:WB;IHC
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Research Areas:Cancer;Metabolism;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:D2HGA2;ICD-M;IDH;IDH2;IDHM;IDHP;IDP;IDPM;Isocitrate dehydrogenase [NADP];mitochondrial;Isocitrate dehydrogenase 2 (NADP+);mitochondrial;mNADP-IDH;NADP(+)-specific ICDH;Oxalosuccinate decarboxylase
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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