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SKU: E-AB-13311_200μL-ES
HSD11B2 Polyclonal Antibody, 200 μL
There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.6 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Cell Biology;Cardiovascular;Metabolism;Signal Transduction
Species Reactivity:Human
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Target Synonym:11 beta HSD2;11 beta hydroxysteroid dehydrogenase type 2;11 DH2;11-beta-HSD2;11-beta-hydroxysteroid dehydrogenase type 2;11-DH2;AME;AME1;Corticosteroid 11 beta dehydrogenase isozyme 2;Corticosteroid 11-beta-dehydrogenase isozyme 2;DHI2;HSD11B2;HSD11K;HSD2;Hydroxysteroid 11 beta dehydrogenase 2;Hydroxysteroid 11 beta dehydrogenase isoenzyme 2;NAD dependent 11 beta hydroxysteroid dehydrogenase;NAD-dependent 11-beta-hydroxysteroid dehydrogenase;SDR9C3;Short chain dehydrogenase/reductase family 9C;member 3
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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