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SKU: AN000380P_25μg-ES
HO1/HMOX1 Polyclonal Antibody, 25 μg
Heme Oxygenase (HO),also known as HMOX,is the rate limiting enzyme in the breakdown of heme into Biliverdin,CO,and iron. There are two major isoforms of this enzyme,HO-1 and HO-2. Both have similar enzymatic activity,however,HO-1 is rapidly inducible,while HO-2 is constitutively expressed. Inducers of HO-1 include cell stressors such as oxidative stress,infection,hypoxia,and cytotoxic agents. The reaction products generated by HO-1 activity are biologically active,and the enzyme has a broad range of putative roles. For instance,Biliverdin is an antioxidant with cytoprotective and anti-inflammatory properties,and CO has the potential to suppress inflammation and apoptosis. Because of these activities,HO-1 has received much attention as a therapeutic target for a range of pathological processes.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:33kDa
Observed Molecular Weight:25kDa
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Shelf Life:12 months
Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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Calculated Molecular Weight:33kDa
Dilution:WB 1:500-1:1000;IHC 1:500-1:1000;ELISA Capture 2-8 μg/mL;ELISA Detector 0.1-0.4 μg/mL
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Application:WB;IHC;ELISA Capture/Detector
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Research Areas:Neuroscience;Cardiovascular;Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Metabolism
Species Reactivity:Human;Mouse
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Target Synonym:Heme oxygenase 1;HO-1;HMOX1;HO;HO1;EC:1.14.14.18
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Buffer:Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
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Clonality:Polyclonal
Conjugation:Unconjugated
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