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SKU: E-AB-31628_20μL-ES
GSK3 alpha/beta Polyclonal Antibody, 20 μL
Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin. GSK-3 is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 is a critical downstream element of the PI3 kinase/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3α and Ser9 of GSK-3βGSK-3 has been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling pathway required for Drosophila, Xenopus and mammalian development. GSK-3 has been shown to regulate cyclin D1 proteolysis and subcellular localization.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:51kDa
Observed Molecular Weight:51,46kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:51kDa
Dilution:WB 1:500-1:2000;IHC 1:100-1:300
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Application:WB;IHC-p
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Research Areas:Cancer;Neuroscience;Signal Transduction;Stem Cells
Species Reactivity:Human;Mouse;Rat
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Target Synonym:GSK3A;Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A;GSK3B;Glycogen synthase kinase-3 beta;GSK-3 beta;Serine/threonine-protein kinase GSK3B
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Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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