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SKU: E-AB-19966_120μL-ES
GRIK2 Polyclonal Antibody, 120 μL
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2) is a Protein Coding gene. Diseases associated with GRIK2 include Autosomal Recessive Non-Syndromic Intellectual Disability and Spinocerebellar Ataxia 11. Among its related pathways are CREB Pathway and Presynaptic function of Kainate receptors. GO annotations related to this gene include protein homodimerization activity and ubiquitin protein ligase binding. An important paralog of this gene is GRIK3.Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1.56 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:25-1:100
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Application:IHC
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Research Areas:Cancer;Neuroscience
Species Reactivity:Human;Mouse;Rat
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Target Synonym:bA487F5.1;EAA4;Excitatory amino acid receptor 4;GLR 6;GLR6;GluK2;GLUK6;GLUR 6;GluR-6;GluR6;Glutamate receptor 6;Glutamate receptor;glutamate receptor form A;glutamate receptor form B;glutamate receptor form C;glutamate receptor form D;glutamate receptor form E;Glutamate receptor ionotropic kainate 2;GRIK 2;GRIK2;GRIK2 protein;GRIK2;ionotropic kainate 2;MRT6
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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