SKU: E-AB-14078_120μL-ES

FADD Polyclonal Antibody, 120 μL

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:0.6 mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IHC 1:50-1:150

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Application:IHC

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Research Areas:Cancer;Cell Biology

Species Reactivity:Human

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Target Synonym:FADD;FADD protein;FADD;Fas (TNFRSF6) associated via death domain;Fas associated via death domain;Fas associating death domain containing protein;Fas associating protein;Fas associating protein with death domain;Fas TNFRSF6 associated via death domain;FAS-associated death domain protein;FAS-associating death domain-containing protein;GIG 3;GIG3;Growth inhibiting gene 3 protein;Growth-inhibiting gene 3 protein;H sapiens mRNA for mediator of receptor induced toxicity;Mediator of receptor induced toxicity;MGC8528;MORT 1;MORT1;Protein FADD

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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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