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SKU: E-AB-14978_120μL-ES
EID1 Polyclonal Antibody, 120 μL
E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.6 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Signal Transduction
Species Reactivity:Human
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Target Synonym:21 kDa pRb associated protein;21 kDa pRb-associated protein;C15orf3;CBP;Chromosome 15 open reading frame 3;CREBBP/EP300 inhibitor 1;CREBBP/EP300 inhibitory protein 1;CRI 1;CRI1;E1A like inhibitor of differentiation;E1A-like inhibitor of differentiation 1;EID 1;EID-1;EID1;EID1;EP300 interacting inhibitor of differentiation 1;EP300-interacting inhibitor of differentiation 1;IRO45620;MGC138883;MGC138884;NB4 apoptosis related protein;PNAS 22;PNAS22;PTD014;Rb and p300 binding protein EID 1;Rb and p300 binding protein EID1;RBP21;Retinoblastoma protein associated protein
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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