- Specification
- Downloads
- Reviews
$524.16
ADD TO CART
SKU: AN006030L_100μL-ES
DPP4/CD26 Polyclonal antibody, 100 μL
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides, and peptide hormones. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV). The soluble CD26 (sCD26) as a tumour marker for the detection of colorectal cancer (CRC) and advanced adenomas. As both a regulatory enzyme and a signalling factor, DPP4 has been evaluated and described in many studies. DPP4 inhibition results in increased blood concentration of the incretin hormones glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). This causes an increase in glucose-dependent stimulation, resulting in a lowering of blood glucose levels. Recent studies have shown that DPP4 inhibitors can induce a significant reduction in glycosylated haemoglobin (HbA(1c)) levels, either as monotherapy or as a combination with other antidiabetic agents. Research has also demonstrated that DPP4 inhibitors portray a very low risk of hypoglycaemia development, and are a new pharmacological class of drugs for treating Type 2 diabetes.
- Regular price
- $524.16 USD
- Sale price
- $524.16 USD
- Regular price
-
ADD TO CART
Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
Safety Performance:
Protection Class:
Sterile Status:
Reconstitution:
Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Battery:
Battery Service Life:
Component:
Technical Specifications
Capacity:
Concentration:1 mg/mL
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:88 kDa
Observed Molecular Weight:120 kDa
Purity:
Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:88 kDa
Dilution:WB 1:1000-1:2000
Driving Motor DC motor:
Em:
Ex:
Endotoxin:
Flow rate [liquid]:
Features and Capabilities
Application:WB
Detection Target:
Detection Type:
Detection Range:
Research Areas:Immunology;Cell Biology;Stem Cells;Cancer;Metabolism
Species Reactivity:Mouse;Rat
Reactivity:
Target Synonym:ADABP Protein;ADCP2 Protein;CD26 Protein;DPPIV Protein;Human;TP103 Protein;DPP;dipeptidylpeptidase;dipeptidyl-peptidase;dipeptidyl peptidase;T-cell activation antigen CD;adenosine deaminase complexing protein;DPP4;ADABP;ADCP2;CD26;DPPIV;TP103;Dipeptidyl peptidase IV;ADCP-2;dipeptidyl-peptidase 4;dipeptidyl peptidase 4;DPP IV;dipeptidylpeptidase 4;T-cell activation antigen CD26;adenosine deaminase complexing protein 2;dipeptidylpeptidase IV;Dipeptidyl peptidase IV (DPP IV)
Test Principle:
Quantitative/Qualitative :
Result Type:
Materials :
Assay Time:
Autoclave component:
Available Rotor Adapters:
Binding Capacity:
Bio-activity:
Bottom Shape:
Bottom Type:
Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Cap Color:
Clonality:Polyclonal
Conjugation:Unconjugated
Coupled Ligand:
Cover Type:
Detection Instrument :
Dispensing Speed:
Display:
Form:
Formulation:
Graduation:
Growth Area:
Powered by Bioz