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SKU: E-AB-11118_200μL-ES
CYP2E1 Polyclonal Antibody, 200 μL
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.5 mg/mL
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Calculated Molecular Weight:57kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:57kDa
Dilution:WB 1:500-1:2000;IHC 1:25-1:100
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Application:WB;IHC
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Research Areas:Cancer;Cardiovascular;Metabolism;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:4-nitrophenol 2-hydroxylase;CP2E1;CPE1;CYP2E;Cyp2e1;CYPIIE1;Cytochrome P450 2E1;Cytochrome P450 isozyme 3A;Cytochrome P450 LM3A;Cytochrome P450;family 2;subfamily e;polypeptide 1;cytochrome P450;subfamily IIE (ethanol-inducible);polypeptide 1;Cytochrome P450;subfamily IIE;Cytochrome P450-ALC;Cytochrome P450-J;Cytochrome P450RLM6;EC 1.14.13.-;EC 1.14.13.n7;Ethanol-inducible P450;Flavoprotein-linked monooxygenase;MGC133529;Microsomal monooxygenase;OTTHUMP00000020813;OTTHUMP00000046571;P450 ALC;P450-J;P450C2E;P450J;P450RLM6;Xenobiotic monooxygenase
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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