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SKU: E-AB-12583_120μL-ES
CHRNA7 Polyclonal Antibody, 120 μL
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.3 mg/mL
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Calculated Molecular Weight:46kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:46kDa
Dilution:WB 1:500-1:2000;IHC 1:25-1:100
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Application:WB;IHC
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Research Areas:Cancer;Metabolism;Neuroscience
Species Reactivity:Human;Mouse;Rat
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Target Synonym:7nAChR;a7 nicotinic acetylcholine receptor;acetylcholine receptor;neuronal nicotinic;alpha-7 subunit;ACHA7;AChR;Acra7;alpha 7 neuronal nicotinic acetylcholine receptor;alpha-7 nicotinic cholinergic receptor subunit;alpha7;cholinergic receptor;neuronal nicotinic;alpha polypeptide 7;cholinergic receptor;nicotinic;alpha 7 (neuronal);cholinergic receptor;nicotinic;alpha 7;cholinergic receptor;nicotinic;alpha polypeptide 7;CHRNA7;CHRNA7-2;NACHRA7;neuronal acetylcholine receptor protein;alpha-7 chain;Neuronal acetylcholine receptor subunit alpha-7
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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