SKU: E-AB-18187_120μL-ES

CEMIP Polyclonal Antibody, 120 μL

Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1.68 mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IHC 1:100-1:300

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Application:IHC

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Research Areas:Cancer;Neuroscience

Species Reactivity:Human;Mouse

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Target Synonym:IR2155535; KIAA1199 protein; OTTHUMP00000185569 ; OTTHUMP00000195036; TMEM2L; Transmembrane protein 2 like

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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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