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SKU: E-AB-13133_200μL-ES
CD59 Polyclonal Antibody, 200 μL
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.5 mg/mL
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Calculated Molecular Weight:14kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:14kDa
Dilution:WB 1:500-1:2000;IHC 1:100-1:300
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Application:WB;IHC
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Research Areas:Cancer;Cardiovascular;Immunology;Signal Transduction;Stem Cells
Species Reactivity:Human
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Target Synonym:16.3A5;1F5;1F5 antigen;20 kDa homologous restriction factor;CD 59;CD_antigen=CD59;CD59;CD59 antigen;CD59 antigen complement regulatory protein ;CD59 antigen p18 20;CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5;EJ16;EJ30;EL32 and G344);CD59 glycoprotein;CD59 molecule;CD59 molecule complement regulatory protein;CD59;Cd59a;Complement regulatory protein;EJ16;EJ30;EL32;FLJ38134;FLJ92039;G344;HRF 20;HRF-20;HRF20;Human leukocyte antigen MIC11;Ly 6 like protein;Lymphocytic antigen CD59/MEM43;MAC inhibitory protein;MAC IP;MAC-inhibitory protein;MAC-IP;MACIF;MACIP;MEM43;MEM43 antigen;Membrane attack complex (MAC) inhibition factor;Membrane attack complex inhibition factor;Membrane inhibitor of reactive lysis;MGC2354;MIC11;MIN1;MIN2;MIN3;MIRL;MSK21;p18 20;Protectin;Surface antigen recognized by monoclonal 16.3A5;T cell activating protein
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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