SKU: E-AB-10614_200μL-ES

CCDC99 Polyclonal Antibody, 200 μL

Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:0.2 mg/mL

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Calculated Molecular Weight:70/59kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:70/59kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Cell Biology

Species Reactivity:Human;Mouse

Reactivity:

Target Synonym:AA409762;Arsenite related gene 1 protein;Arsenite-related gene 1 protein;CCDC 99;Ccdc99;Coiled coil domain containing 99;Coiled-coil domain-containing protein 99;FLJ20364;FLJ40690;hSpindly;MGC124977;Protein Spindly;rhabdomyosarcoma antigen MU RMS 40.4A;Rhabdomyosarcoma antigen MU-RMS-40.4A;Rrhabdomyosarcoma antigen protein MU RMS 40.4A;SPDL1;SPDLY;Spindle apparatus coiled coil domain containing protein 1;Spindle apparatus coiled coil protein 1;Spindly;Spindly homolog

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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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