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SKU: E-AB-13820_60μL-ES
CASP10 Polyclonal Antibody, 60 μL
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.2 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:25-1:100
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Application:IHC
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Research Areas:Cancer;Cell Biology;Metabolism
Species Reactivity:Human
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Target Synonym:ALPS2;Apoptotic protease Mch-4;CASP 10;CASP-10;CASP10;CASPA;Caspase 10 apoptosis related cysteine peptidase;Caspase-10 subunit p12;FADD like ICE2;Fas associated death domain protein;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE 2;FLICE2;ICE like apoptotic protease 4;ICE-like apoptotic protease 4;Interleukin 1B converting enzyme 2;MCH 4
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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