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SKU: E-AB-11008_60μL-ES
BABAM2 Polyclonal Antibody, 60 μL
Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.5 mg/mL
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Calculated Molecular Weight:44kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:44kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:200
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Application:WB;IHC
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Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse;Rat
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Target Synonym:6030405P19Rik;AI429776;B830038C02Rik;Brain and reproductive organ expressed (TNFRSF1A modulator);brain and reproductive organ expressed protein;Brain and reproductive organ-expressed protein;BRCA1 A complex subunit BRE;BRCA1-A complex subunit BRE;BRCA1/BRCA2 containing complex subunit 4;BRCA1/BRCA2 containing complex subunit 45;BRCA1/BRCA2-containing complex subunit 45;BRCC4;BRCC45;bre;BRE
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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