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SKU: E-AB-10699_120μL-ES
ALKBH1 Polyclonal Antibody, 120 μL
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.3 mg/mL
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Calculated Molecular Weight:44kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:44kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse
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Target Synonym:ABH;ABH1;alkB;alkB homolog 1 histone H2A dioxygenase;AlkB;alkylation repair homolog 1 (E. coli);ALKB1;ALKBH;ALKBH1;Alkylated DNA repair protein alkB homolog 1;Alkylation repair homolog 1;Alkylation repair;alkB homolog;Alpha-ketoglutarate-dependent dioxygenase ABH1;DNA lyase ABH1;DNA oxidative demethylase ALKBH1;hABH
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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