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SKU: E-AB-12706_20μL-ES
AGXT Polyclonal Antibody, 20 μL
Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.6 mg/mL
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Calculated Molecular Weight:43kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:43kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Metabolism;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:AGT;AGT1;Agxt;AGXT1;Alanine glyoxylate aminotransferase;Alanine glyoxylate aminotransferase3;Alanine--glyoxylate aminotransferase;EC 2.6.1.44;EC 2.6.1.51;Hepatic peroxisomal alanine glyoxylate aminotransferase;Hepatic peroxisomal alanine:glyoxylate aminotransferase;L alanine glyoxylate aminotransferase 1;MS773;PH1;Serine pyruvate aminotransferase;Serine--pyruvate aminotransferase;Serine--pyruvate aminotransferase;mitochondrial;Serine:pyruvate aminotransferase;SPAT;SPT;SPYA;TLH6
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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