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SKU: E-AB-15513_200μL-ES
ACVR2A Polyclonal Antibody, 200 μL
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1.2 mg/mL
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Calculated Molecular Weight:58kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:58kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Metabolism;Signal Transduction;Stem Cells
Species Reactivity:Human;Mouse;Rat
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Target Synonym:Activin A receptor type IIA;Activin receptor type 2A;Activin receptor type IIA;Activin receptor type-2A;ACTR 2;ACTR IIA;ACTR-IIA;ACTR2;ACTRII;ACTRIIA;Acvr 2;Acvr 2A;Acvr2;ACVR2A;AVR2A;OTTHUMP00000197918
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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