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Código SKU: E-AB-53236_200μL-ES
Anticuerpo policlonal ZFYVE19, 200 μL
ZFYVE19 (dedo de zinc, dominio FYVE que contiene 19), también conocida como MPFYVE (pareja MLL que contiene el dominio FYVE), es una proteína de 471 aminoácidos que contiene un dedo de zinc de tipo FYVE. Expresada en corazón, cerebro, riñón, músculo esquelético e hígado, ZFYVE19 puede participar en eventos de regulación transcripcional celular. Los defectos en el gen que codifica ZFYVE19 se asocian con la leucemia mieloblástica aguda (LMA), un cáncer de la línea mieloide de glóbulos blancos de rápida progresión que se caracteriza por fiebre, anemia, dolor óseo, disnea e infecciones frecuentes. Existen tres isoformas de ZFYVE19 debido a eventos de splicing alternativo.
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