Código SKU: PDER100203_20μg-ES

Proteína EZH1 de rata recombinante (etiqueta His), 20 μg

Proteína del grupo Polycomb (PcG). Subunidad catalítica del complejo PRC2/EED-EZH1, que metila la lisina 27 de la histona H3, lo que provoca la represión transcripcional del gen diana afectado. Es capaz de monometilar, dimetilar y trimetilar la lisina 27 de la histona H3 para formar H3K27me1, H3K27me2 y H3K27me3, respectivamente. Es necesaria para la derivación y la autorrenovación de células madre embrionarias, lo que sugiere que participa en la protección de la identidad de las células madre embrionarias. En comparación con los complejos que contienen EZH1, es menos abundante en las células madre embrionarias, presenta una actividad metiltransferasa débil y desempeña un papel menos crítico en la formación de H3K27me3, necesaria para la identidad y la diferenciación adecuada de las células madre embrionarias.

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Product Specification

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Brands:Elabscience

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