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Código SKU: PDER100228_20μg-ES
Proteína CD109 recombinante de rata (etiqueta His), 20 μg
CD109 es un miembro anclado a GPI de la familia de proteínas de la alfa-2-macroglobulina (A2M) y del complemento. La escisión de las proteínas de la familia A2M en la región cebo activa el enlace tioéster para promover la unión covalente con grupos nucleófilos en moléculas adyacentes. Comparte una identidad de secuencia de aminoácidos del 27-33% con A2M y los factores del complemento C3, C4 y C5. El empalme alterno de CD109 humano genera dos isoformas con deleciones cortas y una truncada en la región cebo. CD109 se expresa en linfocitos T activados y plaquetas, células madre hematopoyéticas, precursores de megacariocitos, células endoteliales vasculares, células basales y mioepiteliales de glándulas secretoras y carcinomas de células escamosas.
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