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Código SKU: PDER100186_20μg-ES
Proteína angiopoyetina-1/ANG1 recombinante de rata (etiqueta His), 20 μg
La angiopoyetina-1 (Ang-1) es una glicoproteína secretada que desempeña un papel fundamental en el desarrollo y mantenimiento del sistema vascular. La vía de señalización angiopoyetina (ANGPT)-TIE2/TEK es esencial para la homeostasis vascular sanguínea y linfática. La ANGPT1 es un potente activador de TIE2, mientras que la ANGPT2 funciona como un agonista/antagonista dependiente del contexto. La angiopoyetina-1 puede proteger contra la hipertensión arterial pulmonar, reducir la extensión de la fibrosis y la remodelación en el miocardio diabético infartado, y favorecer la progresión tumoral y la metástasis.
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