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Código SKU: PKSM041484_20μg-ES
Proteína TNF beta recombinante de ratón (etiqueta His), 20 μg
El factor de necrosis tumoral β (TNF-β) es una proteína secretada que pertenece a la familia de los factores de necrosis tumoral. El TNF-β se une a TNFRSF1A/TNFR1, TNFRSF1B/TNFBR y TNFRSF14/HVEM en forma homotrimérica, y a TNFRSF3/LTBR en forma heterotrimérica con LTB. El TNF-β forma heterotrímeros con la linfotoxina beta, que ancla el TNF-β a la superficie celular. El TNF-β media la respuesta inflamatoria, inmunoestimulante y antiviral, participa en la formación de segundos órganos linfoides durante el desarrollo y participa en la apoptosis. El TNF-β es producido por los linfocitos y es citotóxico para diversas células tumorales in vitro e in vivo.
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